Skyrim Alchemy Profitability Calculator
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The effect Weakness to Frost (45) can be achieved in a potion if you mix these ingredients:

Abecean Longfin
Elves Ear
Fire Salts
Ice Wraith Teeth
White Cap

Here is a list of possible combinations of ingredients:

Abecean Longfin
White Cap		=>Weakness to Frost=>45
  + Small Antlers+ Weakness to Poison, Fortify Restoration+ 190 = 235
  + Human Flesh+ Fortify Sneak, Restore Magicka+ 163 = 208
  + Frost Mirriam+ Fortify Sneak, Ravage Magicka+ 150 = 195
  + Small Pearl+ Fortify Restoration+ 134 = 179
  + Salt Pile+ Fortify Restoration+ 134 = 179
  + Purple Mountain Flower+ Fortify Sneak+ 134 = 179
  + Powdered Mammoth Tusk+ Fortify Sneak+ 134 = 179
  + Hawk Feathers+ Fortify Sneak+ 134 = 179
  + Cyrodilic Spadetail+ Fortify Restoration+ 134 = 179
  + Beehive Husk+ Fortify Sneak+ 134 = 179
  + Sabre Cat Tooth+ Weakness to Poison, Fortify Heavy Armor+ 116 = 161
  + Giant Lichen+ Weakness to Poison, Restore Magicka+ 85 = 130
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 105
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 105
  + Ice Wraith Teeth+ Fortify Heavy Armor+ 60 = 105
  + Pine Thrush Egg+ Weakness to Poison+ 56 = 101
  + Deathbell+ Weakness to Poison+ 56 = 101
  + Chaurus Eggs+ Weakness to Poison+ 56 = 101
  + Bleeding Crown+ Weakness to Poison+ 56 = 101
  + Red Mountain Flower+ Restore Magicka, Ravage Magicka+ 45 = 90
  + Grass Pod+ Restore Magicka, Ravage Magicka+ 45 = 90
  + Vampire Dust+ Restore Magicka+ 29 = 74
  + Taproot+ Restore Magicka+ 29 = 74
  + Pearl+ Restore Magicka+ 29 = 74
  + Mora Tapinella+ Restore Magicka+ 29 = 74
  + Moon Sugar+ Restore Magicka+ 29 = 74
  + Frost Salts+ Restore Magicka+ 29 = 74
  + Fire Salts+ Restore Magicka+ 29 = 74
  + Elves Ear+ Restore Magicka+ 29 = 74
  + Ectoplasm+ Restore Magicka+ 29 = 74
  + Dwarven Oil+ Restore Magicka+ 29 = 74
  + Creep Cluster+ Restore Magicka+ 29 = 74
  + Briar Heart+ Restore Magicka+ 29 = 74
  + Orange Dartwing+ Ravage Magicka+ 16 = 61
  + Lavender+ Ravage Magicka+ 16 = 61
 
Abecean Longfin
Ice Wraith Teeth		=>Weakness to Frost=>45
  + Chaurus Eggs+ Weakness to Poison, Invisibility+ 413 = 458
  + Vampire Dust+ Invisibility+ 357 = 402
  + Nirnroot+ Invisibility+ 357 = 402
  + Luna Moth Wing+ Invisibility+ 357 = 402
  + Crimson Nirnroot+ Invisibility+ 357 = 402
  + Small Antlers+ Weakness to Poison, Fortify Restoration+ 190 = 235
  + Powdered Mammoth Tusk+ Fortify Sneak, Weakness to Fire+ 188 = 233
  + Small Pearl+ Fortify Restoration+ 134 = 179
  + Salt Pile+ Fortify Restoration+ 134 = 179
  + Purple Mountain Flower+ Fortify Sneak+ 134 = 179
  + Human Flesh+ Fortify Sneak+ 134 = 179
  + Hawk Feathers+ Fortify Sneak+ 134 = 179
  + Frost Mirriam+ Fortify Sneak+ 134 = 179
  + Cyrodilic Spadetail+ Fortify Restoration+ 134 = 179
  + Beehive Husk+ Fortify Sneak+ 134 = 179
  + Sabre Cat Tooth+ Weakness to Poison, Fortify Heavy Armor+ 116 = 161
  + Bleeding Crown+ Weakness to Poison, Weakness to Fire+ 110 = 155
  + White Cap+ Fortify Heavy Armor+ 60 = 105
  + Thistle Branch+ Fortify Heavy Armor+ 60 = 105
  + Slaughterfish Scales+ Fortify Heavy Armor+ 60 = 105
  + Pine Thrush Egg+ Weakness to Poison+ 56 = 101
  + Giant Lichen+ Weakness to Poison+ 56 = 101
  + Deathbell+ Weakness to Poison+ 56 = 101
  + Moon Sugar+ Weakness to Fire+ 54 = 99
  + Juniper Berries+ Weakness to Fire+ 54 = 99
  + Frost Salts+ Weakness to Fire+ 54 = 99
 
Abecean Longfin
Fire Salts		=>Weakness to Frost=>45
  + Salt Pile+ Fortify Restoration, Regenerate Magicka+ 337 = 382
  + Taproot+ Restore Magicka, Regenerate Magicka+ 232 = 277
  + Moon Sugar+ Restore Magicka, Regenerate Magicka+ 232 = 277
  + Dwarven Oil+ Restore Magicka, Regenerate Magicka+ 232 = 277
  + Jazbay Grapes+ Regenerate Magicka+ 203 = 248
  + Garlic+ Regenerate Magicka+ 203 = 248
  + Small Antlers+ Weakness to Poison, Fortify Restoration+ 190 = 235
  + Human Flesh+ Fortify Sneak, Restore Magicka+ 163 = 208
  + Small Pearl+ Fortify Restoration+ 134 = 179
  + Purple Mountain Flower+ Fortify Sneak+ 134 = 179
  + Powdered Mammoth Tusk+ Fortify Sneak+ 134 = 179
  + Hawk Feathers+ Fortify Sneak+ 134 = 179
  + Frost Mirriam+ Fortify Sneak+ 134 = 179
  + Cyrodilic Spadetail+ Fortify Restoration+ 134 = 179
  + Beehive Husk+ Fortify Sneak+ 134 = 179
  + Elves Ear+ Resist Fire, Restore Magicka+ 125 = 170
  + Snowberries+ Resist Fire+ 96 = 141
  + Mudcrab Chitin+ Resist Fire+ 96 = 141
  + Fly Amanita+ Resist Fire+ 96 = 141
  + Dragons Tongue+ Resist Fire+ 96 = 141
  + Bone Meal+ Resist Fire+ 96 = 141
  + Giant Lichen+ Weakness to Poison, Restore Magicka+ 85 = 130
  + Sabre Cat Tooth+ Weakness to Poison+ 56 = 101
  + Pine Thrush Egg+ Weakness to Poison+ 56 = 101
  + Deathbell+ Weakness to Poison+ 56 = 101
  + Chaurus Eggs+ Weakness to Poison+ 56 = 101
  + Bleeding Crown+ Weakness to Poison+ 56 = 101
  + White Cap+ Restore Magicka+ 29 = 74
  + Vampire Dust+ Restore Magicka+ 29 = 74
  + Red Mountain Flower+ Restore Magicka+ 29 = 74
  + Pearl+ Restore Magicka+ 29 = 74
  + Mora Tapinella+ Restore Magicka+ 29 = 74
  + Grass Pod+ Restore Magicka+ 29 = 74
  + Frost Salts+ Restore Magicka+ 29 = 74
  + Ectoplasm+ Restore Magicka+ 29 = 74
  + Creep Cluster+ Restore Magicka+ 29 = 74
  + Briar Heart+ Restore Magicka+ 29 = 74
 
Abecean Longfin
Elves Ear		=>Weakness to Frost=>45
  + Small Antlers+ Weakness to Poison, Fortify Restoration+ 190 = 235
  + Human Flesh+ Fortify Sneak, Restore Magicka+ 163 = 208
  + Spider Egg+ Fortify Marksman+ 134 = 179
  + Small Pearl+ Fortify Restoration+ 134 = 179
  + Salt Pile+ Fortify Restoration+ 134 = 179
  + Purple Mountain Flower+ Fortify Sneak+ 134 = 179
  + Powdered Mammoth Tusk+ Fortify Sneak+ 134 = 179
  + Juniper Berries+ Fortify Marksman+ 134 = 179
  + Hawk Feathers+ Fortify Sneak+ 134 = 179
  + Frost Mirriam+ Fortify Sneak+ 134 = 179
  + Cyrodilic Spadetail+ Fortify Restoration+ 134 = 179
  + Canis Root+ Fortify Marksman+ 134 = 179
  + Beehive Husk+ Fortify Sneak+ 134 = 179
  + Fire Salts+ Restore Magicka, Resist Fire+ 125 = 170
  + Snowberries+ Resist Fire+ 96 = 141
  + Mudcrab Chitin+ Resist Fire+ 96 = 141
  + Fly Amanita+ Resist Fire+ 96 = 141
  + Dragons Tongue+ Resist Fire+ 96 = 141
  + Bone Meal+ Resist Fire+ 96 = 141
  + Giant Lichen+ Weakness to Poison, Restore Magicka+ 85 = 130
  + Sabre Cat Tooth+ Weakness to Poison+ 56 = 101
  + Pine Thrush Egg+ Weakness to Poison+ 56 = 101
  + Deathbell+ Weakness to Poison+ 56 = 101
  + Chaurus Eggs+ Weakness to Poison+ 56 = 101
  + Bleeding Crown+ Weakness to Poison+ 56 = 101
  + White Cap+ Restore Magicka+ 29 = 74
  + Vampire Dust+ Restore Magicka+ 29 = 74
  + Taproot+ Restore Magicka+ 29 = 74
  + Red Mountain Flower+ Restore Magicka+ 29 = 74
  + Pearl+ Restore Magicka+ 29 = 74
  + Mora Tapinella+ Restore Magicka+ 29 = 74
  + Moon Sugar+ Restore Magicka+ 29 = 74
  + Grass Pod+ Restore Magicka+ 29 = 74
  + Frost Salts+ Restore Magicka+ 29 = 74
  + Ectoplasm+ Restore Magicka+ 29 = 74
  + Dwarven Oil+ Restore Magicka+ 29 = 74
  + Creep Cluster+ Restore Magicka+ 29 = 74
  + Briar Heart+ Restore Magicka+ 29 = 74